Israel launched airstrikes on the Houthi Security and Intelligence Service Headquarters in Sanaa, Yemen, at approximately 3:32 PM UTC on September 26th, 2025, destroying the main building and severely damaging others. The strikes targeted military objectives, including the Houthi General Staff Command HQ, security and intelligence compounds, public relations headquarters, and military camps. These actions were carried out in response to repeated Houthi attacks against Israel and its civilians, according to an operational statement. The targeted location, identified by coordinates 15.3286, 44.1932, experienced significant destruction, with the main building reportedly destroyed and all other structures severely impacted. The Israeli military stated that the operations were directed at the "security and intelligence apparatus and the military of the Houthi terrorist regime in Sanaa, Yemen." The strikes specifically aimed at facilities where weapons and operatives were identified. This development follows statements from earlier on September 26th, 2025, regarding Israeli Prime Minister Benjamin Netanyahu's invitation to Lebanon for peace talks amidst ongoing tensions. Previous reports also detailed an Israeli airstrike on a Hezbollah precision missile manufacturing site in Lebanon's Beqaa Valley on the same day, attributed to violations of a ceasefire agreement. The context of regional instability is further underscored by ongoing concerns over Iran's nuclear program expansion and its nuclear reactor deal with Russia.